Diabetes exacerbates outcomes in SARS-CoV-2 infections, contributing to increased mortality. Several recent studies suggest that metformin, a widely used antidiabetic drug, may improve survival in COVID-19 patients. Joshi G et al. from Dr. Prasenjit’s lab have revealed critical insights into the increased severity of COVID-19 in diabetic patients and potential therapeutic interventions.
Sepsis is a serious, life-threatening condition that occurs when the body overreacts to a bacterial or viral infection, leading to chronic inflammation, organ damage, and even death. During sepsis, the immune system goes into overdrive, causing a “cytokine storm” where inflammatory chemicals flood the body, leading to severe complications.