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Dr. Ramu S. Vemanna
Associate Professor
  • PhD 2013, Bangalore University, Bangalore, India
  • Post Doc at Noble Research institute, Oklahoma, USA
ramu[dot]vemanna[at]rcb[dot]res[dot]in

Translation mechanisms contributing to plant development and drought stress adaptation

Drought stress tolerance is multigenic in nature. Protein synthesis is affected under drought stress, which, in turn, influences cellular metabolic activities required for optimum functioning. 

Ribosomes are responsible for protein synthesis. However, ribosome biogenesis is a highly orchestrated mechanism involving many proteins for the translation activity of cells. We want to unravel how translational mechanisms regulate the adaptation abilities of plants under changing environmental conditions.

Areas of interest

Protein translational mechanisms in plants.
Extra-ribosomal functions of ribosomal proteins.
Ribosome biogenesis factors in plant growth and development.
Regulatory proteins of ribosome biogenesis.
Drought stress adaptation of plants.

My research focuses on understanding the basis of plant adaptation to drought to improve the productivity of our crops. Under stress conditions, the acquired tolerant traits play a crucial role as a measure of cellular level tolerance. Emphasis is on Ribosomal RNA (rRNA) processing mechanisms, ribosome biogenesis and their assembly factors.

Functional characterisation of the genes involved in these mechanisms and exploring their extra-ribosomal functions and relevance in growth, development and abiotic stress tolerance. Further, we want to unravel how translational regulation contributes to acclimation processes in changing climatic conditions. 

Identifying the relevant cis-elements on ribosomal RNA genes and ribosomal proteins encoding gene promoters and transcription factors involved in their expression and regulation of translational activity has phenomenal significance.

We are also working on developing strategies to improve resistance against bacterial leaf blight disease in rice-causing pathogen Xanthomonas oryzae pv oryzae. We use functional and chemical genomic approaches to improve plant health.

  • Shristi Sharma

    Project JRF

  • Ocean Khajuria

    Trainees

  • Pooja

    Project Fellows

  • Chethan Chauhan

    Project Fellows

  • Kishore Ingole

    Project JRF

  • Mohammad Ahmar Rashid Khan

    Trainee

  • Sai Chandeeramaulee

    Trainee

  • Labeena Usmani

    Trainee

  • Mukund Mendirata

    Project Assistant

  • Dr Chanchal Kumari

    DBT RA

  • Akashata Dawane

    PhD Scholar

  • Subham Agarwal

    Project JRF

  • Libin Thomas

    PhD Scholar

  • Shobhna Yadav

    PhD Scholar

  • Garima Pal

    PhD Scholar

  • Innovative Young Biotechnologist Award- (IYBA), 2016- 2020, DBT India
  • Ramanujan Fellow - DST, SERB -2017-22
  • CSIR-senior research Associate (Scientist pool) -December 2016 to April 2017
  • Fulbright-Nehru Postdoctoral Fellow- Sept 2014 to June 2016
  • Patent file No. 154/CHE/2012, “Selectable marker system”, Ramu S.V, Babitha K.C, Nataraja N Karaba, Udayakumar M,. Indian patent
  • Patent file No. 2646/CHE/2014, “An expression construct and its use for increasing abiotic stress tolerance in a plant cell”, Ramu S.V, Babitha K.C, Sheela. H.S, Prasad, T.G, Tuteja N, Udayakumar M,. Indian patent
  • Patent file No. 4195/CHE/2014, Herbicide tolerant multigene construct, Ramu S.V, Amaranatha, Reddy V, Udayakumar M,. Indian Patent

Selected Publications

  1. Dawane A, Deshpande S, Vijayaraghavreddy P, Vemanna RS. Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice. Plant Physiol Biochem. 2024 Mar 18;208:108513. doi: 10.1016/j.plaphy.2024.108513. Online ahead of print. PMID: 38513519
  2. Pal, G., Ingole, K.D., Yavvari, P.S., Verma, P., Kumari, A., Chauhan, C. Chaudhary D, Srivastava A, Bajaj A, Vemanna RS. Exogenous application of nanocarrier-mediated double-stranded RNA manipulates physiological traits and defence response against bacterial diseases.Molecular Plant Pathology, 2024, ,25, e13417.
  3. Pal G, Bakade R, Deshpande S, Sureshkumar V, Patil SS, Dawane A, Agarwal S, Niranjan V, PrasannaKumar MK, Vemanna RS. (2022). Transcriptomic responses under combined bacterial blight and drought stress in rice reveal potential genes to improve multi-stress tolerance.BMC Plant Biol 22, 349. https://doi.org/10.1186/s12870-022-03725-3
  4. Vanitha PA, Vijayaraghavareddy P, Uttarkar A, Dawane A, Sujitha D, Ashwin V, Babitha KC, Niranjan V, Sheshshayee MS, Anuradha CV, Makarla U, Vemanna RS. (2022) Novel small molecules targeting bZIP23 TF improve stomatal conductance and photosynthesis under mild drought stress by regulating ABA. FEBS J, doi: 10.1111/febs.16461
  5. Karthika V, Babitha K. Chandrashekar, Kiranmai K, Shankar AG, Udayakumar Makarla, and Vemanna S. Ramu, (2021) Disruption in the DNA Mismatch Repair Gene MSH2 by CRISPR-Cas9 in Indica Rice Can Create Genetic Variability. J. Agric. Food Chem. 2021, /doi.org/10.1021/acs.jafc.1c00328

Filed

  1. Patent file No. 2646/CHE/2014, “An expression construct and its use for increasing abiotic stress tolerance in a plant cell”, Ramu S.V, Babitha K.C, Sheela. H.S, Prasad, T.G, Tuteja N, Udayakumar M,. Indian patent
  2. Patent file No. 4195/CHE/2014, Herbicide tolerant multigene construct, Ramu S.V, Amaranatha, Reddy V, Udayakumar.M,. Indian Patent
  3. Application No. 202111038068. A Pro-Transpirants Class Combination. Ramu S Vemanna, PA, Vanitha, NV, Preethi, 2021, Indian Patent
  4. Application number – 202311015285RNP complex for crop protection against bacterial diseases. Pal G, Bajaj A, Bhattacharjee S, Vemanna RS (07 March 2023), Indian patent
  5. Provisional patent filed - 202411062781, TEMP/E-1/72958/2024-DEL Synthetic and natural molecules for crop protection against plant diseases caused by bacteria, and nematode and virus. Garima Pal, Ramu S Vemanna, India Patent.

Granted

  1. 154/CHE/2012, “Selectable marker system”, Ramu S.V, Babitha K.C, Nataraja N Karaba, Udayakumar M,. Indian patent, Granted in 2022.
  2. 202211006352, Pro-transpirants to increase crop productivity, Babitha KC, Veena HM and Ramu S Vemanna 2024 Indian Patent

All Publications

Dr. Ramu S. Vemanna
Associate Professor

Regional Centre for Biotechnology
NCR Biotech Science Cluster
3rd Milestone, Faridabad-Gurgaon Expressway
P.O. Box No. 3, Faridabad - 121 001
Haryana (NCR Delhi), India

no text ramu[dot]vemanna[at]rcb[dot]res[dot]in
no text 91 129-2848713

Dr. Ramu S. Vemanna

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