Plants constantly exposed to stress and oxidative stress is ubiquitous. The downstream effect of oxidative stress in terms of generation of Reactive carbonyl compounds (RCC), glycation products were not explored well in plant biology. This review provides an insight that sequence of events happening in the plants and their influence on plant physiology and subsequent effect on food. Further we also provide few important ways in which plants mitigate these cytotoxic compounds. Overall the study provides insights for scientists to develop strategies to develop healthy food.

Most cells divide through a highly dynamic but tightly regulated process known as mitosis to help the body grow and develop properly. Mistake(s) during mitosis lead to aberrant growth and development, and often to deadly diseases like cancer. One key event early during mitosis is the proper positioning and orientation of the mitotic spindle within the mother cell, a process crucial to decide the proper axis of body growth, organ development and maintenance of stem cells.

Present prospective study is designed to find changes in salivary protein expressions from early to middle phase of term pregnancy. To date, a comprehensive characterization of the longitudinal salivary proteome in pregnancy has not been performed, and here first time we establish an expressional trajectory for modulated proteins in pregnancy. The label free proteomics (SWATH-MS) was performed with maternal saliva (N=20) at 6-13, 18-21, and 26-29 weeks of gestation.

The DNA polymerase module of the Pfprex enzyme (PfpPol) is responsible for duplication of the genome of the apicoplast organelle in the malaria parasite. We show that PfpPol can misincorporate oxidized nucleotides such as 8oxodGTP opposite dA. This event gives rise to transversion mutations that are known to lead to adverse physiological outcomes. The apicoplast genome is particularly vulnerable to the harmful effects of 8oxodGTP due to very high AT content (~ 87%).

Ion channels in particular Calcium (Ca2+) channels play a critical role in physiology by regulating plethora of cellular processes ranging from cell proliferation, differentiation, transcriptional regulation and programmed cell death.

Use of antibiotics is not only developing resistance but also destroying the gut microbiota that we earned since birth. Hence the search for alternative approaches including the use of probiotics is being explored. The probiotics are well known for their beneficial effects, including inhibition of colonization by harmful microbes. One of the vital criteria in choosing probiotics is they must have the ability to attach to the gut lines.

Pictures of Covid-19 waste floating in the sea and rivers, scattered waste outside the garbage bins and stray animals carrying mask in their mouths are in circulation on social media. Low-income countries with weak health systems, crowded megacities and large populations of impoverished people are facing huge challenge to dispose Covid-19 biomedical waste generated every day. Failure to pay attention to the Covid-19 waste management may result in risk of poor outcomes during the pandemic which is far higher among those with comorbidities.

SARS‐CoV‐2 is the causative agent for the ongoing COVID19 pandemic, and this virus belongs to the Coronaviridae family. Like other members of this family, the virus possesses a positive‐sense single‐stranded RNA genome. The genome encodes for the nsp12 protein, which houses the RNA‐dependent‐RNA polymerase (RdRP) activity responsible for the replication of the viral genome. A homology model of nsp12 was prepared using the structure of the SARS nsp12 (6NUR) as a model.

Ribosomes play an integral part in plant growth, development and defense responses. We report that the Ribosomal protein QM/RPL10 and its interacting proteins RNA recognition motif (RRM), RPL30, RPL23, and RPS30 have extra-ribosomal functions and play a role in nonhost disease resistance.

Accurate identification of the translation initiation codon is critical to ensure the synthesis of the correct cellular proteins in the proper amounts. In eukaryotes, translation initiation generally occurs by a cap-dependent scanning mechanism, wherein the small (40S) subunit of the ribosome recruits methionyl initiator tRNA (Met-tRNAi) in a ternary complex (TC) with GTP-bound eukaryotic initiation factor 2 (eIF2), in a reaction stimulated by factors eIF1, eIF1A, and eIF3.